Strategic Design of Alternative Methods to Reduce Animal Testing

QSAR models of safety assessment endpoints allow managers to set priorities for testing and safety assessments even before preliminary animal test data are available. To create models for inhalation safety assessments, the International QSAR Foundation has partnered with the Lake Superior Research Institute at the University of Wisconsin-Superior to compile high-quality inhalation data. The first baseline toxicity model for rodents has been published (here). All data are encoded in the OECD harmonized templates and made searchable as a download to the project sponsors at http://www.uwsuper.edu/lsri; click on Data Library.